L TRYPTOPHAN RELATED EOSINOPHILIA MYALGIA SYNDROME
\ˈɛl tɹˈɪptɒfən ɹɪlˈe͡ɪtɪd ˌiːəsˌɪnəfˈɪli͡ə ma͡ɪˈald͡ʒə sˈɪndɹə͡ʊm], \ˈɛl tɹˈɪptɒfən ɹɪlˈeɪtɪd ˌiːəsˌɪnəfˈɪliə maɪˈaldʒə sˈɪndɹəʊm], \ˈɛ_l t_ɹ_ˈɪ_p_t_ɒ_f_ə_n ɹ_ɪ_l_ˈeɪ_t_ɪ_d ˌiː__ə_s_ˌɪ_n_ə_f_ˈɪ_l_iə m_aɪ__ˈa_l_dʒ_ə s_ˈɪ_n_d_ɹ_əʊ_m]\
Definitions of L TRYPTOPHAN RELATED EOSINOPHILIA MYALGIA SYNDROME
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A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSPINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26 (6):788-93)
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