L TYPE CALCIUM CHANNELS
\ˈɛl tˈa͡ɪp kˈalsi͡əm t͡ʃˈanə͡lz], \ˈɛl tˈaɪp kˈalsiəm tʃˈanəlz], \ˈɛ_l t_ˈaɪ_p k_ˈa_l_s_iə_m tʃ_ˈa_n_əl_z]\
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Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and nonexcitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.
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hydromorphic
- [Greek] Structurally adapted to an aquatic environment, as organs of water plants.