RETINOBLASTOMA
\ɹˌɛtɪnˌə͡ʊblastˈə͡ʊmə], \ɹˌɛtɪnˌəʊblastˈəʊmə], \ɹ_ˌɛ_t_ɪ_n_ˌəʊ_b_l_a_s_t_ˈəʊ_m_ə]\
Definitions of RETINOBLASTOMA
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malignant ocular tumor of retinal cells; usually occurs before the third year of life; composed of primitive small round retinal cells
By Princeton University
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malignant ocular tumor of retinal cells; usually occurs before the third year of life; composed of primitive small round retinal cells
By DataStellar Co., Ltd
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A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
By DataStellar Co., Ltd