MELANOCYTIC MEDULLOBLASTOMA
\mˌɛlɐnəsˈɪtɪk mˌɛdəlˌɒblastˈə͡ʊmə], \mˌɛlɐnəsˈɪtɪk mˌɛdəlˌɒblastˈəʊmə], \m_ˌɛ_l_ɐ_n_ə_s_ˈɪ_t_ɪ_k m_ˌɛ_d_ə_l_ˌɒ_b_l_a_s_t_ˈəʊ_m_ə]\
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A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.
Nearby Words
- melanocyte stimulating hormone release inhibiting factor
- melanocyte stimulating hormone release inhibiting hormone
- melanocyte stimulating hormones
- melanocyte-stimulating hormone
- melanocytes
- Melanocytic Medulloblastoma
- melanocytic medulloblastomas
- melanocytic nevi
- melanocytic nevus
- melanocytic vestibular schwannoma
- melanocytic vestibular schwannomas