CONGENITAL TOXOPLASMA INFECTION
\kənd͡ʒˈɛnɪtə͡l tˈɒksəplˌazməɹ ɪnfˈɛkʃən], \kəndʒˈɛnɪtəl tˈɒksəplˌazməɹ ɪnfˈɛkʃən], \k_ə_n_dʒ_ˈɛ_n_ɪ_t_əl t_ˈɒ_k_s_ə_p_l_ˌa_z_m_ə_ɹ ɪ_n_f_ˈɛ_k_ʃ_ə_n]\
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Prenatal protozoal infection with TOXOPLASMA gondii which is associated with injury to the developing fetal nervous system. The severity of this condition is related to the stage of pregnancy during which the infection occurs; first trimester infections are associated with a greater degree of neurologic dysfunction. Clinical features include HYDROCEPHALUS; MICROCEPHALY; deafness; cerebral calcifications; SEIZURES; and psychomotor retardation. Signs of a systemic infection may also be present at birth, including fever, rash, and hepatosplenomegaly. (From Adams et al., Principles of Neurology, 6th ed, p735)
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