TAY SACHS DISEASE
\tˈe͡ɪ sˈaks dɪzˈiːz], \tˈeɪ sˈaks dɪzˈiːz], \t_ˈeɪ s_ˈa_k_s d_ɪ_z_ˈiː_z]\
Definitions of TAY SACHS DISEASE
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a hereditary disorder of lipid metabolism occuring most frequently in individuals of eastern European Jewish descent; accumulation of lipids in nervous tissue results in death in early childhood
By DataStellar Co., Ltd
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a hereditary disorder of lipid metabolism occuring most frequently in individuals of Jewish descent in eastern Europe; accumulation of lipids in nervous tissue results in death in early childhood
By Princeton University
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An autosomal recessive inherited gangliosidosis characterized by the onset in the first 6 months of life of an exaggerated startle response, delay in psychomotor development, hypotonia (followed by spasticity), visual loss, and a macular cherry red spot. Hexosaminidase A (see BETA-N-ACETYLHEXOSAMINIDASE) is deficient, leading to the accumulation of GM2 ganglioside in neurons of the central nervous system and retina. This condition is strongly associated with Askenazic Jewish ancestory. (Menkes, Textbook of Pediatric Neurology, 5th ed pp89-96)
By DataStellar Co., Ltd
