MALIGNANT CARCINOID SYNDROME
\məlˈɪɡnənt kˈɑːsɪnˌɔ͡ɪd sˈɪndɹə͡ʊm], \məlˈɪɡnənt kˈɑːsɪnˌɔɪd sˈɪndɹəʊm], \m_ə_l_ˈɪ_ɡ_n_ə_n_t k_ˈɑː_s_ɪ_n_ˌɔɪ_d s_ˈɪ_n_d_ɹ_əʊ_m]\
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A symptom complex associated with CARCINOID TUMOR and characterized by attacks of severe flushing of the skin, diarrheal watery stools, bronchoconstriction, sudden drops in blood pressure, edema, and ascites. The carcinoid tumors are usually located in the gastrointestinal tract and metastasize to the liver. Symptoms are caused by tumor secretion of serotonin, prostaglandins, and other biologically active substances. Cardiac manifestations constitute CARCINOID HEART DISEASE. (Dorland, 27th ed; Stedman, 25th ed)
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