LIPEMIA CLEARING FACTOR
\la͡ɪpˈiːmi͡ə klˈi͡əɹɪŋ fˈaktə], \laɪpˈiːmiə klˈiəɹɪŋ fˈaktə], \l_aɪ_p_ˈiː_m_iə k_l_ˈiə_ɹ_ɪ_ŋ f_ˈa_k_t_ə]\
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An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinemia Type I. (Dorland, 27th ed) EC 3.1.1.34.
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