HEPARIN BINDING FIBROBLAST GROWTH FACTOR CLASS I
\hˈɛpəɹˌɪn bˈa͡ɪndɪŋ fˈɪbɹəblˌast ɡɹˈə͡ʊθ fˈaktə klˈas ˈa͡ɪ], \hˈɛpəɹˌɪn bˈaɪndɪŋ fˈɪbɹəblˌast ɡɹˈəʊθ fˈaktə klˈas ˈaɪ], \h_ˈɛ_p_ə_ɹ_ˌɪ_n b_ˈaɪ_n_d_ɪ_ŋ f_ˈɪ_b_ɹ_ə_b_l_ˌa_s_t ɡ_ɹ_ˈəʊ_θ f_ˈa_k_t_ə k_l_ˈa_s ˈaɪ]\
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A 17 kD single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of ANGIOGENESIS. It binds to HEPARIN, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 2).
By DataStellar Co., Ltd
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