HEPARIN BINDING GROWTH FACTOR CLASS II
\hˈɛpəɹˌɪn bˈa͡ɪndɪŋ ɡɹˈə͡ʊθ fˈaktə klˈas ɹˌə͡ʊmən tˈuː], \hˈɛpəɹˌɪn bˈaɪndɪŋ ɡɹˈəʊθ fˈaktə klˈas ɹˌəʊmən tˈuː], \h_ˈɛ_p_ə_ɹ_ˌɪ_n b_ˈaɪ_n_d_ɪ_ŋ ɡ_ɹ_ˈəʊ_θ f_ˈa_k_t_ə k_l_ˈa_s ɹ_ˌəʊ_m_ə_n_ t_ˈuː]\
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A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).
By DataStellar Co., Ltd
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Nearby Words
- heparan sulfate
- heparan sulfate proteoglycan
- heparin
- heparin antagonists
- heparin binding fibroblast growth factor class i
- Heparin Binding Growth Factor Class II
- heparin binding growth factor, class i
- heparin binding protein 44
- heparin binding protein p30
- heparin binding protein, 39 kda
- heparin clearing factor