APRAXIA OF PHONATION
\ɐpɹˈe͡ɪksi͡əɹ ɒv fənˈe͡ɪʃən], \ɐpɹˈeɪksiəɹ ɒv fənˈeɪʃən], \ɐ_p_ɹ_ˈeɪ_k_s_iə_ɹ ɒ_v f_ə_n_ˈeɪ_ʃ_ə_n]\
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A group of cognitive disorders characterized by the inability to perform previously learned skills that cannot be attributed to deficits of motor or sensory function. The two major subtypes of this condition are ideomotor (see APRAXIA, IDEOMOTOR) and ideational apraxia, which refers to loss of the ability to mentally formulate the processes involved with performing an action. For example, dressing apraxia may result from an inability to mentally formulate the act of placing clothes on the body. Apraxias are generally associated with lesions of the dominant PARIETAL LOBE and supramarginal gyrus. (From Adams et al., Principles of Neurology, 6th ed, pp56-7)
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Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.