TRANSMITTER UPTAKE INHIBITORS, NEURONAL
\tɹansmˈɪtəɹ ˈʌpte͡ɪk ɪnhˈɪbɪtəz], \tɹansmˈɪtəɹ ˈʌpteɪk ɪnhˈɪbɪtəz], \t_ɹ_a_n_s_m_ˈɪ_t_ə_ɹ ˈʌ_p_t_eɪ_k ɪ_n_h_ˈɪ_b_ɪ_t_ə_z]\
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Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects.
By DataStellar Co., Ltd
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