MU CONOTOXIN
\mˈuː kənˈɒtəksˌɪn], \mˈuː kənˈɒtəksˌɪn], \m_ˈuː k_ə_n_ˈɒ_t_ə_k_s_ˌɪ_n]\
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Peptide neurotoxins from the marine fish-hunting snails of the genus Conus. They contain 13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide bonds. There are three types of conotoxins, omega-, alpha-, and mu-. OMEGA-CONOTOXINS inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore the release of ACETYLCHOLINE. Alpha-conotoxins inhibit the postsynaptic acetylcholine receptor. Mu-conotoxins prevent the generation of muscle action potentials. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
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