LACUNAR DEMENTIAS
\lˈakənˌɑː dɪmˈɛnʃəz], \lˈakənˌɑː dɪmˈɛnʃəz], \l_ˈa_k_ə_n_ˌɑː d_ɪ_m_ˈɛ_n_ʃ_ə_z]\
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Loss of higher cortical functions with retained awareness due to multiple cortical or subcortical CEREBRAL INFARCTION. Memory, judgement, attention span, and impulse control are often impaired, and may be accompanied by PSEUDOBULBAR PALSY, hemiparesis, reflex abnormalities, and other signs of localized neurologic dysfunction. (From Adams et al., Principles of Neurology, 6th ed, p1060)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.