KININASE II INHIBITORS
\kˈɪnɪnˌe͡ɪs ɹˌə͡ʊmən tˈuː ɪnhˈɪbɪtəz], \kˈɪnɪnˌeɪs ɹˌəʊmən tˈuː ɪnhˈɪbɪtəz], \k_ˈɪ_n_ɪ_n_ˌeɪ_s ɹ_ˌəʊ_m_ə_n_ t_ˈuː ɪ_n_h_ˈɪ_b_ɪ_t_ə_z]\
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A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
By DataStellar Co., Ltd
