DNA THERAPY
\dˌiːˌɛnˈe͡ɪ θˈɛɹəpi], \dˌiːˌɛnˈeɪ θˈɛɹəpi], \d_ˌiː__ˌɛ_n_ˈeɪ θ_ˈɛ_ɹ_ə_p_i]\
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The introduction of new genes into cells for the purpose of treating disease by restoring or adding gene expression. Techniques include insertion of retroviral vectors, transfection, homologous recombination, and injection of new genes into the nuclei of single cell embryos. The entire gene therapy process may consist of multiple steps. The new genes may be introduced into proliferating cells in vivo (e.g., bone marrow) or in vitro (e.g., fibroblast cultures) and the modified cells transferred to the site where the gene expression is required. Gene therapy may be particularly useful for treating enzyme deficiency diseases, hemoglobinopathies, and leukemias and may also prove useful in restoring drug sensitivity, particularly for leukemia.
By DataStellar Co., Ltd
Word of the day
Mustagh Range
- a mountain range in northern Kashmir; an extension of the Hindu Kush; contains 2nd highest peak