DNA TOPOISOMERASE
\dˌiːˌɛnˈe͡ɪ tˈɒpɔ͡ɪsˌə͡ʊmɹe͡ɪz], \dˌiːˌɛnˈeɪ tˈɒpɔɪsˌəʊmɹeɪz], \d_ˌiː__ˌɛ_n_ˈeɪ t_ˈɒ_p_ɔɪ_s_ˌəʊ_m_ɹ_eɪ_z]\
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DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix.
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.