Definitions of c fms Genes

  1. Family of genes originally isolated from the Susan McDonough strain of feline sarcoma virus ( SARCOMA VIRUSES, FELINE). The proto- oncogene fms ( c- fms) codes for the MCSF receptor ( RECEPTOR, MACROPHAGE COLONY- STIMULATING FACTOR). The oncogene fms ( v- fms) codes for ONCOGENE PROTEIN GP1409( V- FMS) which is a mutated form of the MCSF. The human c- fms gene is located between 5q33. 2 and 5q33. 3.