Definitions of c erbB 3 Protein

  1. A cell surface protein- tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive homology to and can heterodimerize with the EGF Receptor ( RECEPTOR, EPIDERMAL GROWTH FACTOR) and the erbB- 2 receptor ( RECEPTOR, ERBB- 2). Overexpression of the erbB- 3 receptor is associated with tumorigenesis. EC 2. 7. 11.-.