BRAIN BENIGN NEOPLASM
\bɹˈe͡ɪn bɪnˈa͡ɪn nˈiːə͡ʊplˌazəm], \bɹˈeɪn bɪnˈaɪn nˈiːəʊplˌazəm], \b_ɹ_ˈeɪ_n b_ɪ_n_ˈaɪ_n n_ˈiː__əʊ_p_l_ˌa_z_ə_m]\
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Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.