\ˌe͡ɪsˌiːˈiː ɪnhˈɪbɪtəz], \ˌeɪsˌiːˈiː ɪnhˈɪbɪtəz], \ˌeɪ_s_ˌiː__ˈiː_ ɪ_n_h_ˈɪ_b_ɪ_t_ə_z]\
Definitions of ACE INHIBITORS
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A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
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