AMINOTRANSFERASES
\ɐmˈɪnətɹɐnsfˌɜːɹe͡ɪzɪz], \ɐmˈɪnətɹɐnsfˌɜːɹeɪzɪz], \ɐ_m_ˈɪ_n_ə_t_ɹ_ɐ_n_s_f_ˌɜː_ɹ_eɪ_z_ɪ_z]\
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A subclass of enzymes of the transferase class that catalyze the transfer of an amino group from a donor (generally an amino acid) to an acceptor (generally a 2-keto acid). Most of these enzymes are pyridoxyl phosphate proteins. (Dorland, 28th ed) EC 2.6.1.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.