AMINOTRIAZOLE
\ɐmˈɪnətɹˌɪɐzˌə͡ʊl], \ɐmˈɪnətɹˌɪɐzˌəʊl], \ɐ_m_ˈɪ_n_ə_t_ɹ_ˌɪ__ɐ_z_ˌəʊ_l]\
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A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.