WEGENERS GRANULOMATOSIS
\wˈɛd͡ʒənəz ɡɹˌanjʊlˌɒmɐtˈə͡ʊsɪs], \wˈɛdʒənəz ɡɹˌanjʊlˌɒmɐtˈəʊsɪs], \w_ˈɛ_dʒ_ə_n_ə_z ɡ_ɹ_ˌa_n_j_ʊ_l_ˌɒ_m_ɐ_t_ˈəʊ_s_ɪ_s]\
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A multisystem disease chiefly affecting males, characterized by necrotizing granulomatous vasculitis involving the upper and lower respiratory tracts, glomerulonephritis, and variable degrees of systemic, small vessel vasculitis, which is generally considered to represent an aberrant hypersensitivity reaction to an unknown antigen. (Dorland, 27th ed)
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
Nearby Words
- weft
- weftage
- wefte
- wegener
- wegener granulomatosis
- Wegeners Granulomatosis
- wegner's disease
- wegner's disease's sign
- wegotism
- wehadinc
- wehnelt's interrupter