WEGENER GRANULOMATOSIS
\wˈɛd͡ʒənə ɡɹˌanjʊlˌɒmɐtˈə͡ʊsɪs], \wˈɛdʒənə ɡɹˌanjʊlˌɒmɐtˈəʊsɪs], \w_ˈɛ_dʒ_ə_n_ə ɡ_ɹ_ˌa_n_j_ʊ_l_ˌɒ_m_ɐ_t_ˈəʊ_s_ɪ_s]\
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A multisystem disease chiefly affecting males, characterized by necrotizing granulomatous vasculitis involving the upper and lower respiratory tracts, glomerulonephritis, and variable degrees of systemic, small vessel vasculitis, which is generally considered to represent an aberrant hypersensitivity reaction to an unknown antigen. (Dorland, 27th ed)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- weezel
- weft
- weftage
- wefte
- wegener
- Wegener Granulomatosis
- wegeners granulomatosis
- wegner's disease
- wegner's disease's sign
- wegotism
- wehadinc