V FOS ONCOGENES
\vˈiː fˈɒs ˈɒnkə͡ʊd͡ʒˌiːnz], \vˈiː fˈɒs ˈɒnkəʊdʒˌiːnz], \v_ˈiː f_ˈɒ_s ˈɒ_n_k_əʊ_dʒ_ˌiː_n_z]\
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Retrovirus-associated DNA sequences (fos) originally isolated from the Finkel-Biskis-Jinkins (FBJ-MSV) and Finkel-Biskis-Reilly (FBR-MSV) murine sarcoma viruses. The proto-oncogene protein c-fos codes for a nuclear protein which is involved in growth-related transcriptional control. The insertion of c-fos into FBJ-MSV or FBR-MSV induces osteogenic sarcomas in mice. The human c-fos gene is located at 14q21-31 on the long arm of chromosome 14.
By DataStellar Co., Ltd
