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Definitions of v fms Protein

  1.   Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus SM FeSV The oncogene protein v fms lacks sequences which in the highly homologous proto oncogene protein c fms CSF 1 receptor normally serve to regulate its tyrosine kinase activity The missing sequences in v fms mimic the effect of ligand and lead to constitutive cell growth The protein gp120 v fms is post translationally modified to generate gp140 v fms