V FMS PROTEIN
\vˈiː ˌɛfˌɛmˈɛs pɹˈə͡ʊtiːn], \vˈiː ˌɛfˌɛmˈɛs pɹˈəʊtiːn], \v_ˈiː_ ˌɛ_f_ˌɛ_m_ˈɛ_s p_ɹ_ˈəʊ_t_iː_n]\
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Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120 (v-fms) is post-translationally modified to generate gp140 (v-fms).
By DataStellar Co., Ltd
Word of the day
Quinones
- Hydrocarbon rings which contain two moieties position. They can be substituted in any position except at the ketone groups.