SECOND MALIGNANCIES
\sˈɛkənd məlˈɪɡnənsɪz], \sˈɛkənd məlˈɪɡnənsɪz], \s_ˈɛ_k_ə_n_d m_ə_l_ˈɪ_ɡ_n_ə_n_s_ɪ_z]\
Sort: Oldest first
-
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.