MCGF 2
\ˌɛmsˌiːd͡ʒˌiːˈɛf tˈuː], \ˌɛmsˌiːdʒˌiːˈɛf tˈuː], \ˌɛ_m_s_ˌiː_dʒ_ˌiː__ˈɛ_f t_ˈuː]\
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Soluble factor produced by activated T-lymphocytes that causes proliferation and differentiation of B-cells. Interleukin-4 induces the expression of class II major histocompatibility complex and Fc receptors on B-cells. It also acts on T-lymphocytes, mast cell lines, and several other hematopoietic lineage cells including granulocyte, megakaryocyte, and erythroid precursors, as well as macrophages.
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