MARSHMALLOW FLUFF
\mˈɑːʃmɐlˌə͡ʊ flˈʌf], \mˈɑːʃmɐlˌəʊ flˈʌf], \m_ˈɑː_ʃ_m_ɐ_l_ˌəʊ f_l_ˈʌ_f]\
Word of the day
ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.