KARL ERDMANN EDLER

\kˈɑːl ˈɜːdman ˈɛdlə], \kˈɑːl ˈɜːdman ˈɛdlə], \k_ˈɑː_l ˈɜː_d_m_a_n ˈɛ_d_l_ə]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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