HIGH MOBILITY GROUP BOX DOMAINS
\hˈa͡ɪ mə͡ʊbˈɪlɪti ɡɹˈuːp bˈɒks dəmˈe͡ɪnz], \hˈaɪ məʊbˈɪlɪti ɡɹˈuːp bˈɒks dəmˈeɪnz], \h_ˈaɪ m_əʊ_b_ˈɪ_l_ɪ_t_i ɡ_ɹ_ˈuː_p b_ˈɒ_k_s d_ə_m_ˈeɪ_n_z]\
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DNA-binding domains present in proteins of the HMG-box superfamily including the archetypal HMGB PROTEINS, a number of sequence specific TRANSCRIPTION FACTORS, and other DNA-BINDING PROTEINS. The domains consist of 70-80 amino acids that form an L-shaped fold from three alpha-helical segments. The domain has the capacity to recognize and/or induce specific DNA structures and effect the accessibility of the DNA to other proteins involved in transcription, recombination, or DNA repair. (Note that not all HIGH MOBILITY GROUP PROTEINS contain this domain.)
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.
Nearby Words
- high lows
- high mallow
- high mass
- high minus low (hml)
- high mobility group (nonhistone chromosomal) protein 2
- High Mobility Group Box Domains
- high mobility group box proteins
- high mobility group chromosomal proteins
- high mobility group i(y) protein
- high mobility group nucleosomal binding proteins
- high mobility group proteins