ENDOMETRIAL STROMAL SARCOMA
\ˌɛndə͡ʊmˈɛtɹɪəl stɹˈə͡ʊmə͡l sɑːkˈə͡ʊmə], \ˌɛndəʊmˈɛtɹɪəl stɹˈəʊməl sɑːkˈəʊmə], \ˌɛ_n_d_əʊ_m_ˈɛ_t_ɹ_ɪ__ə_l s_t_ɹ_ˈəʊ_m_əl s_ɑː_k_ˈəʊ_m_ə]\
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A highly malignant neoplasm of the endometrium, arising from the endometrial stroma. It represents one type of stromal tumor, the other being endolymphatic stromal myosis. They are differentiated on the basis of the number of mitoses per 10 high power fields: endometrial stromal sarcoma has 10 or more mitoses, endolymphatic stromal myosis fewer. Stroma sarcoma is seen most often between the ages of 45 and 50. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1146)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.