EMILIA PARDO BAZAN

\ɛmˈɪli͡ə pˈɑːdə͡ʊ bˈazən], \ɛmˈɪli‍ə pˈɑːdə‍ʊ bˈazən], \ɛ_m_ˈɪ_l_iə p_ˈɑː_d_əʊ b_ˈa_z_ə_n]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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