CYTOTOXIC BRAIN EDEMA
\sˌa͡ɪtətˈɒksɪk bɹˈe͡ɪn ˈɛdɪmə], \sˌaɪtətˈɒksɪk bɹˈeɪn ˈɛdɪmə], \s_ˌaɪ_t_ə_t_ˈɒ_k_s_ɪ_k b_ɹ_ˈeɪ_n ˈɛ_d_ɪ_m_ə]\
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Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8 (6):301-6)
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Dopamine Acetyltransferase
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