CHICKEN INHIBITOR OF METALLOPROTEINASES 3
\t͡ʃˈɪkɪn ɪnhˈɪbɪtəɹ ɒv mˈɛtə͡lˌɒpɹə͡ʊtˌɪne͡ɪsɪz θɹˈiː], \tʃˈɪkɪn ɪnhˈɪbɪtəɹ ɒv mˈɛtəlˌɒpɹəʊtˌɪneɪsɪz θɹˈiː], \tʃ_ˈɪ_k_ɪ_n ɪ_n_h_ˈɪ_b_ɪ_t_ə_ɹ ɒ_v m_ˈɛ_t_əl_ˌɒ_p_ɹ_əʊ_t_ˌɪ_n_eɪ_s_ɪ_z θ_ɹ_ˈiː]\
Definitions of CHICKEN INHIBITOR OF METALLOPROTEINASES 3
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A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21 kD, nonglycosylated protein. TIMP-3 does not show a high degree of structural similarity unlike TIMP-1 and TIMP-2 which are structurally similar. However, it does possess a high degree of structural similarity with that of chicken TIMP-3 (ChIMP-3). Human TIMP-3 is of particular concern because of its potential role in cancer, arthritis, and eye diseases.
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