ANTIBODY DIVERSITIES
\ˈantɪbˌɒdi da͡ɪvˈɜːsɪtiz], \ˈantɪbˌɒdi daɪvˈɜːsɪtiz], \ˈa_n_t_ɪ_b_ˌɒ_d_i d_aɪ_v_ˈɜː_s_ɪ_t_i_z]\
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The phenomenon of immense variability characteristic of antibodies, which enables the immune system to react specifically against the essentially unlimited kinds of antigens it encounters. Antibody diversity is accounted for by three main theories: 1) the Germ Line Theory, which holds that each antibody-producing cell has genes coding for all possible antibody specificities, but expresses only the one stimulated by antigen; 2) the Somatic Mutation Theory, which holds that antibody-producing cells contain only a few genes, which produce antibody diversity by mutation; and 3) the Gene Rearrangement Theory, which holds that antibody diversity is generated by the rearrangement of variable region gene segments during the differentiation of the antibody-producing cells.
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Platidiam
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Nearby Words
- antibody dependent cell cytotoxicity
- antibody dependent cell cytoxicities
- antibody dependent cell cytoxicity
- antibody dependent enhancement
- antibody dependent enhancements
- Antibody Diversities
- antibody diversity
- antibody enzyme technic, unlabeled
- antibody enzyme technique, unlabeled
- antibody producing cell
- antibody producing cells