ADULT SPINAL MUSCULAR ATROPHY
\ˈadʌlt spˈa͡ɪnə͡l mˈʌskjʊləɹ ˈatɹəfi], \ˈadʌlt spˈaɪnəl mˈʌskjʊləɹ ˈatɹəfi], \ˈa_d_ʌ_l_t s_p_ˈaɪ_n_əl m_ˈʌ_s_k_j_ʊ_l_ə_ɹ ˈa_t_ɹ_ə_f_i]\
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A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
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