OMEGA NITROARGININE
\ə͡ʊmˈe͡ɪɡə nˌa͡ɪtɹə͡ʊˈɑːd͡ʒɪnˌa͡ɪn], \əʊmˈeɪɡə nˌaɪtɹəʊˈɑːdʒɪnˌaɪn], \əʊ_m_ˈeɪ_ɡ_ə n_ˌaɪ_t_ɹ_əʊ_ˈɑː_dʒ_ɪ_n_ˌaɪ_n]\
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An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200 (4):451-6)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.