JOSEF JIRI KOLAR

\d͡ʒˈə͡ʊsəf d͡ʒˈi͡əɹi kˈə͡ʊlə], \d‍ʒˈə‍ʊsəf d‍ʒˈi‍əɹi kˈə‍ʊlə], \dʒ_ˈəʊ_s_ə_f dʒ_ˈiə_ɹ_i k_ˈəʊ_l_ə]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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