GUANINE NUCLEOTIDE COUPLING PROTEIN

\ɡwˈɑːna͡ɪn njˈuːklɪˌɒta͡ɪd kˈʌplɪŋ pɹˈə͡ʊtiːn], \ɡwˈɑːna‍ɪn njˈuːklɪˌɒta‍ɪd kˈʌplɪŋ pɹˈə‍ʊtiːn], \ɡ_w_ˈɑː_n_aɪ_n n_j_ˈuː_k_l_ɪ__ˌɒ_t_aɪ_d k_ˈʌ_p_l_ɪ_ŋ p_ɹ_ˈəʊ_t_iː_n]\

Definitions of GUANINE NUCLEOTIDE COUPLING PROTEIN

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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