GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS

\ɡwˈɑːna͡ɪn njˈuːklɪˌɒta͡ɪd dɪsˈə͡ʊsɪˈe͡ɪʃən ɪnhˈɪbɪtəz], \ɡwˈɑːna‍ɪn njˈuːklɪˌɒta‍ɪd dɪsˈə‍ʊsɪˈe‍ɪʃən ɪnhˈɪbɪtəz], \ɡ_w_ˈɑː_n_aɪ_n n_j_ˈuː_k_l_ɪ__ˌɒ_t_aɪ_d d_ɪ_s_ˈəʊ_s_ɪ__ˈeɪ_ʃ_ə_n ɪ_n_h_ˈɪ_b_ɪ_t_ə_z]\

Definitions of GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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