FIBRINOGEN
\fˈɪbɹɪnəd͡ʒən], \fˈɪbɹɪnədʒən], \f_ˈɪ_b_ɹ_ɪ_n_ə_dʒ_ə_n]\
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Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
By DataStellar Co., Ltd
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A globulin of the blood-plasma which is converted into the coagulated protein, fibrin, by the action of fibrin-ferment in the presence of a salt of calcium; it is this change which produces coagulation of the blood.
By Stedman, Thomas Lathrop
By William R. Warner
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A soluble constituent of blood which yields fibrin and produces coagulation.
By Henderson, I. F.; Henderson, W. D.
By Willam Alexander Newman Dorland
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