ACTIVATED FACTOR XII
\ˈaktɪvˌe͡ɪtɪd fˈaktə ɹˌə͡ʊmən twˈɛlv], \ˈaktɪvˌeɪtɪd fˈaktə ɹˌəʊmən twˈɛlv], \ˈa_k_t_ɪ_v_ˌeɪ_t_ɪ_d f_ˈa_k_t_ə ɹ_ˌəʊ_m_ə_n_ t_w_ˈɛ_l_v]\
Sort: Oldest first
-
Activated form of factor XII. In the initial event in the intrinsic pathway of blood coagulation, kallikrein (with cofactor HIGH MOLECULAR WEIGHT KININOGEN) cleaves factor XII to XIIa. Factor XIIa is then further cleaved by kallikrein, plasmin, and trypsin to yield smaller factor XII fragments (Hageman-Factor fragments). These fragments increase the activity of prekallikrein to kallikrein but decrease the procoagulant activity of factor XII.
By DataStellar Co., Ltd
Word of the day
Snake's-head
- Guinea-hen flower; -- so called in England because its spotted petals resemble the scales of a snake's head.