STEELE RICHARDSON OLSZEWSKI SYNDROME

\stˈiːl ɹˈɪt͡ʃədsən ɒlszjˈuːskɪ sˈɪndɹə͡ʊm], \stˈiːl ɹˈɪt‍ʃədsən ɒlszjˈuːskɪ sˈɪndɹə‍ʊm], \s_t_ˈiː_l ɹ_ˈɪ_tʃ_ə_d_s_ə_n ɒ_l_s_z_j_ˈuː_s_k_ɪ s_ˈɪ_n_d_ɹ_əʊ_m]\

Definitions of STEELE RICHARDSON OLSZEWSKI SYNDROME

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2010 - Medical Dictionary Database
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Sporadic Retinoblastoma

  • A malignant arising nuclear layer retina that is most primary eye in children. The tumor tends to occur early childhood or infancy present at birth. majority are sporadic, but condition may be transmitted as autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS; STRABISMUS; visual loss represent common clinical characteristics this condition. (From DeVita et al., Cancer: Principles Practice Oncology, 5th ed, p2104)
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