PTH (1 84)
\pˌiːtˌiːˈe͡ɪt͡ʃ wˈɒn ˈe͡ɪtifˈɔː], \pˌiːtˌiːˈeɪtʃ wˈɒn ˈeɪtifˈɔː], \p_ˌiː_t_ˌiː__ˈeɪ_tʃ__ w_ˈɒ_n ˈeɪ_t_i_f_ˈɔː]\
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Polypeptide hormones (84 amino acid residues) secreted by the parathyroid glands, which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts, indirectly promote increased intestinal absorption of calcium, and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates. It is a major regulator of bone metabolism. Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low. Its action is opposed by calcitonin. (Dorland, 28th ed)
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