PERIODIC DISEASE
\pˌi͡əɹɪˈɒdɪk dɪzˈiːz], \pˌiəɹɪˈɒdɪk dɪzˈiːz], \p_ˌiə_ɹ_ɪ__ˈɒ_d_ɪ_k d_ɪ_z_ˈiː_z]\
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An autosomal recessive inherited disease characterized by episodic fever, severe abdominal pain, pleurisy, arthritis, and a characteristic ankle rash. Disease flare-ups tend to last 3 days, and individuals are asymptomatic between attacks. Orchitis, a benign recurrent MENINGITIS, headaches, and amyloid nephropathy may also occur. (From Medicine (Baltimore) 1998 Jul;77 (4):268-97)
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