OBSTRUCTIVE LIVER CIRRHOSIS
\ɒbstɹˈʌktɪv lˈɪvə sɜːɹˈə͡ʊsɪs], \ɒbstɹˈʌktɪv lˈɪvə sɜːɹˈəʊsɪs], \ɒ_b_s_t_ɹ_ˈʌ_k_t_ɪ_v l_ˈɪ_v_ə s_ɜː_ɹ_ˈəʊ_s_ɪ_s]\
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Liver cirrhosis in which there is interference with intrahepatic bile flow. It includes primary biliary cirrhosis, an intrahepatic disturbance of bile secretion affecting predominantly middle-aged women and with segmental destruction and, later, absence of septal bile ducts (cirrhosis is the end stage); and secondary biliary cirrhosis, which is produced by prolonged mechanical obstruction of large intrahepatic or extrahepatic bile ducts.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.