NICARDIPINE
\nˈɪkɑːdˌɪpa͡ɪn], \nˈɪkɑːdˌɪpaɪn], \n_ˈɪ_k_ɑː_d_ˌɪ_p_aɪ_n]\
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A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.