NEOCARZINOSTATIN
\nˈiːə͡ʊkˌɑːzɪnˌɒstɐtˌɪn], \nˈiːəʊkˌɑːzɪnˌɒstɐtˌɪn], \n_ˈiː__əʊ_k_ˌɑː_z_ɪ_n_ˌɒ_s_t_ɐ_t_ˌɪ_n]\
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An antitumor isolate from the culture filtrate of the F-41 variant of Streptomyces carzinostaticus. It is a protein of known amino acid sequence with a molecular weight of approximately 11,500 and possessing a regulatory function on the metabolism of DNA. In this process, that is first an inhibition of DNA biosynthesis followed by the degradation of DNA, zinostatin functions in a manner analogous to that of the much higher molecular weight antibiotic MITOMYCIN. Zinostatin is also a potent cytostatic agent active against gram-positive organisms.
By DataStellar Co., Ltd
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Snake's-head
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